Migration, Urbanization, and the Microbiomes of the Galapagos Giant Tortoises

The loss of biological diversity stands as one of the most severe human-caused global environmental problems. Effectively addressing this challenge necessitates adopting a
Planetary Health perspective built on understanding the interconnections of people, animals, and the environment. Host-associated microbiomes play a pivotal role in host nutrient uptake, immune response, development, and behavior; therefore, microbiome-informed intervention holds promises as a new conservation strategy. To design microbiome-informed interventions in natural habitats requires a comprehensive understanding of the interplay between microbiome, environment, and host fitness of free-living animals.

This Here and Next project will characterize the diversity and distribution of microorganisms associated with the iconic, endangered species Giant Tortoises (Chelonoidis spp.) in the Galápagos archipelago. Further, we will investigate the effects of anthropogenic interferences on the Giant Tortoise microbiomes and explore whether and how host phylogeny plays a role in the microbiome composition and associations. The findings of this study will serve as a foundational step in incorporating the microbiome into the conservation toolset for Giant Tortoise and other species. Researchers will collaborate with the Institute for Conservation Medicine at the St. Louis Zoo.

Research Team

Fangqiong Ling, WashU (McKelvey School of Engineering)
Jonathan Losos, WashU (Biology)